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Acute myeloid leukemia with t(8;21)(q22;q22) translocation
5 associated genes
No signs/symptoms info
PROTEIN INTERACTIONS: 2
Cherubism
1 OMIM reference -
1 associated gene
13 signs/symptoms
Acute myeloid leukemia with t(8;21)(q22;q22) translocation
Cherubism

CEBPA
(UniProt - OMIM)
 SH3BP2
(UniProt - OMIM)
FLT3
(UniProt - OMIM)
KIT
(UniProt - OMIM)
RUNX1
(UniProt - OMIM)
RUNX1T1
(UniProt - OMIM)

INTERACTOME
ASSOCIATIONS
(click on a score value to see the evidence)
KIT
FLT3
(0.72)
(0.63)
SH3BP2
SH3BP2


Citations in the biomedical literature:


Acute myeloid leukemia with t(8;21)(q22;q22) translocation
CEBPA FLT3 KIT RUNX1 RUNX1T1
Cherubism
SH3BP2



Acute myeloid leukemia with t(8;21)(q22;q22) translocation
Cherubism

Synonym(s):
(no synonyms)

Synonym(s):
- CRBM
Classification (Orphanet):
- Rare hematologic disease
- Rare oncologic disease
Classification (Orphanet):
- Rare bone disease
- Rare developmental defect during embryogenesis
- Rare genetic disease
- Rare odontologic disease
Classification (ICD10):
- Neoplasms -
Classification (ICD10):
- Diseases of the digestive system -
Epidemiological data:
(no data available)
Epidemiological data:
Class of prevalence: unknown
Average age onset: childhood
Average age of death: normal
Type of inheritance: autosomal dominant
External references:
No OMIM references
No MeSH references
External references:
1 OMIM reference -
1 MeSH reference: D002636
Cherubism

Very frequent
- Autosomal dominant inheritance
- Bone / osseous neoplasm / tumor / carcinoma / cancer
- Enlargment of jaw / large jaw
- High cheek bones

Frequent
- Abnormal dentition / dental position / implantation / unerupted / dental ankylosis
- Anodontia / oligodontia / hypodontia
- Tooth shape anomaly

Occasional
- Abnormal cry / voice / phonation disorder / nasal speech
- Apnea / sleep apnea
- Feeding disorder / dysphagia / swallowing / sucking disorder / esophageal dyskinesia
- Optic nerve anomaly / optic atrophy / anomaly of the papilla
- Proptosis / exophthalmos
- Visual loss / blindness / amblyopia


Acute myeloid leukemia with t(8;21)(q22;q22) translocation

(no data available)